Can you use adobe with truecrypt

Are you able to use adobe with and encrypted file system using truecrypt? Below is taken from their site: "Note: The issue described below does not affect you if you use TrueCrypt 5.1 or later and a non-cascade encryption algorithm (i.e., AES, Serpent, or Twofish).* The issue also does not affect you if you do not use system encryption (pre-boot authentication)." So does this mean that...